Interactions between lithium and renal transport of Krebs cycle intermediates.
نویسندگان
چکیده
منابع مشابه
Sodium-coupled transporters for Krebs cycle intermediates.
Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate are transferred across plasma membranes of cells by secondary active transporters that couple the downhill movement of sodium to the concentrative uptake of substrate. Several transporters have been identified in isolated membrane vesicles and cells based on their functional properties, suggesting the existence of at ...
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A preparation of streptolysin 0 partially purified from Streptococcus pyogenes strain C203S was shown to contain at least two distinct entities (Carlson et al., 1956): streptolysin 0 which brings about a marked loss of myocardial contractile power in isolated, perfused guinea pig, rabbit, and rat hearts (Kellner et al., 1956), and a diphosphopyridine nucleotidase which specifically attacks diph...
متن کاملEffect of Streptolysin 0 on the Utilization of Some Krebs Cycle Intermediates by Aerobacter Aerogenes Sue
A preparation of streptolysin 0 partially purified from Streptococcus pyogenes strain C203S was shown to contain at least two distinct entities (Carlson et al., 1956): streptolysin 0 which brings about a marked loss of myocardial contractile power in isolated, perfused guinea pig, rabbit, and rat hearts (Kellner et al., 1956), and a diphosphopyridine nucleotidase which specifically attacks diph...
متن کاملThe life-extending gene Indy encodes an exchanger for Krebs-cycle intermediates.
A longevity gene called Indy (for 'I'm not dead yet'), with similarity to mammalian genes encoding sodium-dicarboxylate cotransporters, was identified in Drosophila melanogaster. Functional studies in Xenopus oocytes showed that INDY mediates the flux of dicarboxylates and citrate across the plasma membrane, but the specific transport mechanism mediated by INDY was not identified. To test wheth...
متن کاملThin layer chromatography of Krebs cycle acids.
A systematic appraisal of a large number of solvent systems was carried out for the separation of lactic, pyruvic and 3-hydroxybutyric acids and all of the KREBS cycle acids, except oxalosuccinic, using silica gel G and cellulose thin layer Chromatographie plates. Four solvent systems which allowed separation of various combinations of acids are described and the limits of this method of separa...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 1982
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.79.23.7514